Description of a technique for the analysis of antineuraminidase antibodies oriented to H2N2 and H3N2 influenza virus strains
Identifieur interne : 002A21 ( Main/Exploration ); précédent : 002A20; suivant : 002A22Description of a technique for the analysis of antineuraminidase antibodies oriented to H2N2 and H3N2 influenza virus strains
Auteurs : J. Drescher [Allemagne]Source :
- Archives of Virology [ 0304-8608 ] ; 1978-03-01.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (analyse), Poulets (immunologie), Recombinaison génétique, Sialidase (génétique), Sialidase (immunologie), Sous-type H2N2 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Sérums immuns, Tests sérologiques (), Virus de la grippe A (génétique), Virus de la grippe A (immunologie).
- MESH :
- analyse : Anticorps antiviraux.
- génétique : Sialidase, Virus de la grippe A.
- immunologie : Poulets, Sialidase, Virus de la grippe A.
- Animaux, Recombinaison génétique, Sous-type H2N2 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Sérums immuns, Tests sérologiques.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (analysis), Chickens (immunology), Immune Sera, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H3N2 Subtype, Influenza A virus (genetics), Influenza A virus (immunology), Neuraminidase (genetics), Neuraminidase (immunology), Recombination, Genetic, Serologic Tests (methods).
- MESH :
- chemical , analysis : Antibodies, Viral.
- genetics : Influenza A virus, Neuraminidase.
- immunology : Chickens, Influenza A virus, Neuraminidase.
- methods : Serologic Tests.
- Teeft :
- Animals, Antibody, Antibody concentration unit, Antibody mixtures, Antibody response, Antibody titration, Antigenic, Antigenic relationship, Antineuraminidase, Antineuraminidase antibodies, Antineuraminidase antibody mixtures, Antiserum, Corresponding ratio, Different classes, Different titer ratios, Enzyme inhibition test, Enzyme inhibition titers, Experimental conditions, Federal republic, Further experience, Hemagglutinating viruses, Hemagglutinin, Hong kong, Immune Sera, Influenza, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H3N2 Subtype, Influenza virus, Influenza virus infection, Influenza virus strains, Influenza virus vaccines, Inhibition tests, Kong virus, Neuraminidase, Neuraminidases, Photometric, Photometric methods, Ratio titer, Reciprocal serum dilutions, Recombinant, Recombination, Genetic, Reference antisera, Reference sera, Regression lines, Serum dilution, Serum dilutions, Serum mixture, Serum mixtures, Significant antigenic difference, Test sera, Titer, Titer ratios, Titration, Virus, Virus concentrations, Virus strains.
Abstract
Summary: A method for the analysis of mixtures of antineuraminidase (AN) antibodies oriented to antigenically different neuraminidases of H2N2 and H3N2 influenza virus strains is described. The method is based on the finding that the different classes of AN antibodies give different titer ratios when reacting with the recombinants A/Bel/42 (H0)-A/Sing/1/57 (N2) and A/equine/Prague/1/56 (Heq 1)-A/Hong Kong/1/68 (N2) and a mixture of both recombinants. These titer ratios are determined under the experimental conditions of the photometric ACU (antibody concentration unit) method for a series of reference sera and test sera. By mathematical treatment of these data an exact analysis of AN antibodies of test sera is achieved. This paper gives a detailed description of the conduct of the test and summarizes the results of experiments designed to assess the accuracy of analysis.
Url:
DOI: 10.1007/BF01317288
Affiliations:
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Le document en format XML
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(génétique)</term><term>Virus de la grippe A (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A virus</term><term>Neuraminidase</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sialidase</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Poulets</term><term>Sialidase</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Chickens</term><term>Influenza A virus</term><term>Neuraminidase</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Serologic Tests</term></keywords><keywords scheme="Teeft" 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sérologiques</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: A method for the analysis of mixtures of antineuraminidase (AN) antibodies oriented to antigenically different neuraminidases of H2N2 and H3N2 influenza virus strains is described. The method is based on the finding that the different classes of AN antibodies give different titer ratios when reacting with the recombinants A/Bel/42 (H0)-A/Sing/1/57 (N2) and A/equine/Prague/1/56 (Heq 1)-A/Hong Kong/1/68 (N2) and a mixture of both recombinants. These titer ratios are determined under the experimental conditions of the photometric ACU (antibody concentration unit) method for a series of reference sera and test sera. By mathematical treatment of these data an exact analysis of AN antibodies of test sera is achieved. This paper gives a detailed description of the conduct of the test and summarizes the results of experiments designed to assess the accuracy of analysis.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Basse-Saxe</li></region><settlement><li>Hanovre</li></settlement></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Drescher, J" sort="Drescher, J" uniqKey="Drescher J" first="J." last="Drescher">J. Drescher</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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